Question 1

Are these shipped with a freezer pack? And also what state are they shipped from?

Accepted Answer

Yes, they're shipped with a freezer pack.  Here's the response I got from SeekingHealth:
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Bobbi (Seeking Health)
Sep 4, 9:04 AM PDT
Hello John,

Thank you for contacting Seeking Health. Our Probiotics have been tested to withstand high temperatures for up to 6 days at a time without losing any viability, so they are fine through the shipping process. You can read more about our testing below:

Long-Term Stability and Expiration: All of our ProBiota products have been freeze-dried to extend the products shelf life. Our products are freeze dried according to strict guidelines, and undergo routine survival studies to ensure viability after freeze-drying. 
We recommend refrigerating the ProBiota products to ensure maximum potency and shelf life, however the ProBiota products may be left at room temperature for days and even weeks without a great loss of viable organisms.  If kept at average room temperature, ProBiota products will remain potent for 4 - 6 months. At higher temperatures (86 F), they will maintain potency for 1 - 2 months.
More specifically, long term testing with our products over two years while stored at 39, 73, and 86 degrees Fahrenheit has been completed. At 73 degrees the ProBiota products began to have a loss of colony counts after one to two months depending on the strain. While these products should not be subjected to high temperatures, being exposed to room temperature and higher for a few days will only result in small losses of organisms. Shipping these products with ice packs and/or expedited shipping methods is recommended (but not required), especially in warmer months and climates, but it is not cause for concern if the ice packs have melted by delivery. 
Exposure to heat is not the only element that can degrade the ProBiota products; moisture and exposure to air are also detrimental.  Most probiotics are anaerobic; they live in an absence of oxygen, and so limiting exposure by keeping them in their sealed dry container with the provided desiccant is ideal. Again, our ProBiota products are freeze dried to minimize the degradation caused by oxygen, and by keeping the ProBiota refrigerated in a sealed and dry container you will maximize the shelf life and potency of your ProBiota product.
Short-Term High Heat Stability: Testing was performed on our ProBiota line to determine how long probiotics could be exposed to high temperatures and remain at label claim. Our probiotics are able to withstand temperatures of 104 degrees Fahrenheit for up to 6 days without losing label claim potency. During the summer months, we recommend ice packs during shipping (and/or expedited shipping) to account for any time during mailing that may be at very high temperatures. The ice packs will almost always arrive melted, which is not a concern, as the ice packs have done their part by extending the colder temperature during shipping. However, ice packs are not a mandatory part of our shipping procedure as the probiotics are rarely at these high temperatures for a extended period of time.

I hope this is helpful, please let me know if I can assist you further.

Kind Regards,
Bobbi (Seeking Health)

Question 2

I am going on a trip so can’t refrigerate them—is there a similar nonrefrigerated version I can take with me?

Accepted Answer

Gee, I don’t refrigerate mine at all.  Haven’t noticed any issues or difference.

Question 3

are these enteric coated? if not, how do they survive in order to get to your small intestine?

Accepted Answer

Probiota HistaminX is not enteric coated. The Capsule is designed to break down much slower than typical capsules in order to make its way to the GI tract. -Seeking Health Staff

Question 4

Are these supposed to be refrigerated?

Accepted Answer

I’m not sure; usually these items need to be refrigerated, but I’ve not done so and have still experienced very good results.

Seeking Health ProBiota HistaminX, 10 Billion CFU Low-Histamine Probiotic Supplement for Gut Health, Microbiome Balance, Digestive Comfort for Histamine Intolerance, Vegan & Vegetarian (60 Capsules)

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